5E3 circuit and a modern Celestion Blue speaker in solid pine cabinet.
Click here for photos and info on the build.
Nick Armenta playing the Custom Deluxe with a strat:
Andy Sonsky playing an Eric Johnson Strat with Lindy Fralin pickups into the Custom 5E3 Tweed Deluxe. Volume cranked to full. Line6 DL4 used at some point. The amp ompletely bottoms out - farty and blatty with the volume cranked - but that's part of the Tweed charm! I have heard it called the "sweating pig" tone:
Nick Armenta playing the Tweed Deluxe with The Ryan Hunt Band: